Protein carbonylation.

  title={Protein carbonylation.},
  author={Yuichiro J Suzuki and Marina Carini and David Butterfield},
  journal={Antioxidants & redox signaling},
  volume={12 3},
Protein carbonylation is a type of protein oxidation that can be promoted by reactive oxygen species. It usually refers to a process that forms reactive ketones or aldehydes that can be reacted by 2,4-dinitrophenylhydrazine (DNPH) to form hydrazones. Direct oxidation of side chains of lysine, arginine, proline, and threonine residues, among other amino acids, in the ‘‘primary protein carbonylation’’ reaction produces DNPH detectable protein products (11, 15, 23). DNPH derivatizable protein… CONTINUE READING
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