Protein carbonylation as a major hallmark of oxidative damage: update of analytical strategies.

@article{Fedorova2014ProteinCA,
  title={Protein carbonylation as a major hallmark of oxidative damage: update of analytical strategies.},
  author={Maria Fedorova and Ravi Chand Bollineni and Ralf Hoffmann},
  journal={Mass spectrometry reviews},
  year={2014},
  volume={33 2},
  pages={79-97}
}
Protein carbonylation, one of the most harmful irreversible oxidative protein modifications, is considered as a major hallmark of oxidative stress-related disorders. Protein carbonyl measurements are often performed to assess the extent of oxidative stress in the context of cellular damage, aging and several age-related disorders. A wide variety of analytical techniques are available to detect and quantify protein-bound carbonyls generated by metal-catalyzed oxidation, lipid peroxidation or… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 54 extracted citations

Similar Papers

Loading similar papers…