Protein-based organelles in bacteria: carboxysomes and related microcompartments

  title={Protein-based organelles in bacteria: carboxysomes and related microcompartments},
  author={T. Yeates and C. Kerfeld and S. Heinhorst and G. Cannon and J. Shively},
  journal={Nature Reviews Microbiology},
  • T. Yeates, C. Kerfeld, +2 authors J. Shively
  • Published 2008
  • Biology, Medicine
  • Nature Reviews Microbiology
  • Many bacteria contain intracellular microcompartments with outer shells that are composed of thousands of protein subunits and interiors that are filled with functionally related enzymes. These microcompartments serve as organelles by sequestering specific metabolic pathways in bacterial cells. The carboxysome, a prototypical bacterial microcompartment that is found in cyanobacteria and some chemoautotrophs, encapsulates ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) and carbonic… CONTINUE READING
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    • 81
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    • 120
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    • 363
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    • 202
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    Carboxysomes and ribulose bisphosphate carboxylase/oxygenase.
    • G. Codd
    • Biology, Medicine
    • Advances in microbial physiology
    • 1988
    • 40
    Polyhedral organelles compartmenting bacterial metabolic processes
    • T. Bobik
    • Biology, Medicine
    • Applied Microbiology and Biotechnology
    • 2005
    • 130
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