Protein array of Coxiella burnetii probed with Q fever sera

@article{Wang2013ProteinAO,
  title={Protein array of Coxiella burnetii probed with Q fever sera},
  author={Xile Wang and Xiaolu Xiong and Stephen R. Graves and John Stenos and Bohai Wen},
  journal={Science China Life Sciences},
  year={2013},
  volume={56},
  pages={453-459}
}
Coxiella burnetii is the etiological agent of Q fever. To identify its major seroreactive proteins, a subgenomic protein array was developed. A total of 101 assumed virulence-associated recombinant proteins of C. burnetii were probed with sera from mice experimentally infected with C. burnetii and sera from Q fever patients. Sixteen proteins were recognized as major seroreactive antigens by the mouse sera. Seven of these 16 proteins reacted positively with at least 45% of Q fever patient sera… 
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