Protein arginine methylation in mammals: who, what, and why.

Abstract

The covalent marking of proteins by methyl group addition to arginine residues can promote their recognition by binding partners or can modulate their biological activity. A small family of gene products that catalyze such methylation reactions in eukaryotes (PRMTs) works in conjunction with a changing cast of associated subunits to recognize distinct… (More)
DOI: 10.1016/j.molcel.2008.12.013

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