Protein and energy metabolism in type 1 diabetes.


Profound metabolic changes occur in people with type 1 diabetes mellitus during insulin deprivation. These include an increase in basal energy expenditure and reduced mitochondrial function. In addition, protein metabolism is significantly affected during insulin deprivation. A greater increase in whole-body protein breakdown than protein synthesis occurs… (More)
DOI: 10.1016/j.clnu.2009.09.001


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