Protein aggregation, metals and oxidative stress in neurodegenerative diseases.

Abstract

There is clear evidence implicating oxidative stress in the pathology of many different neurodegenerative diseases. ROS (reactive oxygen species) are the primary mediators of oxidative stress and many of the aggregating proteins and peptides associated with neurodegenerative disease can generate hydrogen peroxide, a key ROS, apparently through interactions… (More)

Topics

2 Figures and Tables

Slides referencing similar topics