Protein accumulation in traumatic brain injury

  title={Protein accumulation in traumatic brain injury},
  author={Douglas H. Smith and Kunihiro Uryu and Kathryn E. Saatman and John Q. Trojanowski and T K Mcintosh},
  journal={NeuroMolecular Medicine},
Traumatic brain injury (TBI) is one of the most devastating diseases in our society, accounting for a high percentage of mortality and disability. A major consequence of TBI is the rapid and long-term accumulation of proteins. This process largely reflects the interruption of axonal transport as a result of extensive axonal injury. Although many proteins are found accumulating after TBI, three have received particular attention; β-amyloid precursor protein and its proteolytic products, amyloid… CONTINUE READING
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