Protein Tyrosine Kinase Panel As a Tool for Anticancer Drug Design

  title={Protein Tyrosine Kinase Panel As a Tool for Anticancer Drug Design},
  author={T. Ya. Rakitina and O. V. Yudkina and E L Smirnova and A. V. Lipkin},
  booktitle={Acta naturae},
The discovery of the pharmaceutical potential of small molecule inhibitors of oncogenic protein tyrosine kinases is one of the directions in target therapy in oncology. Presently, investigations aiming at developing new therapeutically important inhibitors have to be based on a combination of computational and experimental approaches including biochitalicical, cell-based or in silico screening and the study of the three-dimensional structure of the kinase active center, in complex with an… CONTINUE READING

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