Protein Translocation: The Sec61/SecYEG Translocon Caught in the Act


The Sec61/SecYEG complex mediates both the translocation of newly synthesized proteins across the membrane and the integration of transmembrane segments into the lipid bilayer. New cryo-electron microscopy studies show ribosome-channel complexes in action and reveal their repertoire of conformational states. 
DOI: 10.1016/j.cub.2014.02.051

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