Protein Ser/Thr phosphatases--the ugly ducklings of cell signalling.

  title={Protein Ser/Thr phosphatases--the ugly ducklings of cell signalling.},
  author={David L. Brautigan},
  journal={The FEBS journal},
  volume={280 2},
This review traces the historical origins and conceptual developments leading to the current state of knowledge of the three superfamilies of protein Ser/Thr phosphatases. 'PR enzyme' was identified as an enzyme that inactivates glycogen phosphorylase, although it took 10 years before this ugly duckling was recognized for its true identity as a protein Ser/Thr phosphatase. Ethanol denaturation for purification in the 1970s yielded a phosphatase that exhibited broad specificity, which was… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 42 extracted citations


Publications referenced by this paper.
Showing 1-10 of 177 references

Similar Papers

Loading similar papers…