Protein S-glutathionylation: from current basics to targeted modifications

@article{Popov2014ProteinSF,
  title={Protein S-glutathionylation: from current basics to targeted modifications},
  author={Doina Popov},
  journal={Archives Of Physiology And Biochemistry},
  year={2014},
  volume={120},
  pages={123 - 130}
}
  • D. Popov
  • Published 1 October 2014
  • Biology, Chemistry
  • Archives Of Physiology And Biochemistry
Abstract The interaction between antioxidant glutathione and the free thiol in susceptible cysteine residues of proteins leads to reversible protein S-glutathionylation. This reaction ensures cellular homeostasis control (as a common redox-dependent post-translational modification associated with signal transduction) and intervenes in oxidative stress-related cardiovascular pathology (as initiated by redox imbalance). The purpose of this review is to evaluate the recent knowledge on protein S… 
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