Protein S-Nitrosylation: Determinants of Specificity and Enzymatic Regulation of S-Nitrosothiol-Based Signaling.

@article{Stomberski2018ProteinSD,
  title={Protein S-Nitrosylation: Determinants of Specificity and Enzymatic Regulation of S-Nitrosothiol-Based Signaling.},
  author={Colin T Stomberski and Douglas T. Hess and Jonathan S. Stamler},
  journal={Antioxidants & redox signaling},
  year={2018}
}
SIGNIFICANCE Protein S-nitrosylation, the oxidative modification of cysteine by nitric oxide (NO) to form protein S-nitrosothiols (SNOs), mediates redox-based signaling that conveys, in large part, the ubiquitous influence of NO on cellular function. S-nitrosylation regulates protein activity, stability, localization, and protein-protein interactions across myriad physiological processes, and aberrant S-nitrosylation is associated with diverse pathophysiologies. Recent Advances: It is recently… CONTINUE READING

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…