Protein Profile and Morphological Alterations in Penumbra after Focal Photothrombotic Infarction in the Rat Cerebral Cortex

@article{Uzdensky2016ProteinPA,
  title={Protein Profile and Morphological Alterations in Penumbra after Focal Photothrombotic Infarction in the Rat Cerebral Cortex},
  author={Anatoly B. Uzdensky and Svetlana V. Demyanenko and Grigory M. Fedorenko and Tayana Lapteva and Alexej Fedorenko},
  journal={Molecular Neurobiology},
  year={2016},
  volume={54},
  pages={4172-4188}
}
After ischemic stroke, cell damage propagates from infarct core to surrounding tissues (penumbra). To reveal proteins involved in neurodegeneration and neuroprotection in penumbra, we studied protein expression changes in 2-mm ring around the core of photothrombotic infarct induced in the rat brain cortex by local laser irradiation after administration of Bengal Rose. The ultrastructural study showed edema and degeneration of neurons, glia, and capillaries. Morphological changes gradually… CONTINUE READING
6 Citations
70 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 70 references

The role of TMP21 in trafficking and amyloid-β precursor protein (APP) processing in Alzheimer’s disease

  • K Bromley-Brits
  • SongW
  • 2012
Highly Influential
4 Excerpts

Cellular and molecular mechanisms of photodynamic therapy

  • AB Uzdensky
  • 2010
Highly Influential
1 Excerpt

Similar Papers

Loading similar papers…