Protein Modules Conserved Since LUCA

  title={Protein Modules Conserved Since LUCA},
  author={Yehoshua Sobolevsky and Edward N. Trifonov},
  journal={Journal of Molecular Evolution},
Universal scale of the sequence conservation has been recently introduced based on omnipresence of the protein sequence motifs across species. A large spectrum of short sequences, up to eight residues has been found to reside in all or almost all prokaryotic organisms. By this discovery a principally novel quantitative approach is introduced to the problem of reconstruction of the last universal common ancestor (LUCA). The most conserved elements (protein modules) with defined structures and… CONTINUE READING

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