Protein L. A novel bacterial cell wall protein with affinity for Ig L chains.

@article{Bjrck1988ProteinLA,
  title={Protein L. A novel bacterial cell wall protein with affinity for Ig L chains.},
  author={Lars Bj{\"o}rck},
  journal={Journal of immunology},
  year={1988},
  volume={140 4},
  pages={1194-7}
}
A novel Ig-binding protein has been isolated from the surface of bacteria belonging to the anaerobic species Peptococcus magnus. To solubilize the protein, peptococci were treated with different proteolytic enzymes (papain, pepsin, and trypsin) or with mutanolysin, a bacteriolytic agent known to digest the cell walls of streptococci. Papain, trypsin, and mutanolysin all solubilized peptides showing affinity for radiolabeled human IgG in Western blot analysis. Compared with papain and trypsin… CONTINUE READING
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