Protein Kinase C Family Members as a Target for Regulation of Blood–Brain Barrier Na,K,2Cl-Cotransporter During In Vitro Stroke Conditions and Nicotine Exposure

Abstract

The aim of the study is to identify specific protein kinase C (PKC) isoforms involvement in K+ transport mediated at altered blood–brain barrier (BBB) response to stroke conditions with prior nicotine exposure, which provides ways to intervene pharmacologically in PKC-mediated molecular pathways that could lead to effective treatment for smoking stroke… (More)
DOI: 10.1007/s11095-005-9143-2

Topics

7 Figures and Tables