Protein Kinase C-Dependent Potentiation of Intracellular Calcium Influx by 1 Receptor Agonists in Rat Hippocampal Neurons

@inproceedings{Monnet2003ProteinKC,
  title={Protein Kinase C-Dependent Potentiation of Intracellular Calcium Influx by 1 Receptor Agonists in Rat Hippocampal Neurons},
  author={F. Monnet and Marie-Pierre Morin-Surun and J Leger and Laurent Combettes},
  year={2003}
}
Intracellular calcium concentration ([Ca ]i) plays a major role in neuronal excitability, especially that triggered by the N-methylD-aspartate (NMDA)-sensitive glutamatergic receptor. We have previously shown that 1 receptor agonists potentiate NMDA receptor-mediated neuronal activity in the hippocampus and recruit Ca -dependent second messenger cascades (e.g., protein kinase C; PKC) in brainstem motor structures. The present study therefore assessed whether the potentiating action of 1… CONTINUE READING
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