Protein Folding In Vivo: Unraveling Complex Pathways

  title={Protein Folding In Vivo: Unraveling Complex Pathways},
  author={J. L. Johnson and Elizabeth A Craig},
polypeptides and rebinding of nonnative species in the central cavity of GroEL (reviewed by Fenton and HorFolding of proteins in a test tube is a private affair. wich, 1997). Protein folding in a cell is another matter entirely. In the For a number of years the predominant model for an complex milieu of the cell, the conditionsof temperature, in vivo protein folding pathway has been the sequential pH, and ionic strength are restricted, and the concentraaction of Hsp70s (with DnaJs) and… CONTINUE READING

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