Protein Depth Calculation and the Use for Improving Accuracy of Protein Fold Recognition

@article{Xu2013ProteinDC,
  title={Protein Depth Calculation and the Use for Improving Accuracy of Protein Fold Recognition},
  author={Dong Xu and Hua Li and Yonghui Zhang},
  journal={Journal of computational biology : a journal of computational molecular cell biology},
  year={2013},
  volume={20 10},
  pages={805-16}
}
Protein structure and function are largely specified by the distribution of different atoms and residues relative to the core and surface of the molecule. Relative depths of atoms therefore are key attributions that have been widely used in protein structure modeling and function annotation. However, accurate calculation of depth is time consuming. Here, we developed an algorithm which uses Euclidean distance transform (EDT) to convert the target protein structure into a 3D gray-scale image… CONTINUE READING