Protein-DNA recognition.

  title={Protein-DNA recognition.},
  author={Carl O. Pabo and Robert T. Sauer},
  journal={Annual review of biochemistry},
Several general principles emerge from the studies of Cro, lambda repressor, and CAP. The DNA-binding sites are recognized in a form similar to B-DNA. They do not form cruciforms or other novel DNA structures. There seem to be proteins that bind left-handed Z-DNA (87) and DNA in other conformations, but it remains to be seen how these structures are… CONTINUE READING