Protein Arginine Methyltransferases (PRMTs): Promising Targets for the Treatment of Pulmonary Disorders

@inproceedings{Zakrzewicz2012ProteinAM,
  title={Protein Arginine Methyltransferases (PRMTs): Promising Targets for the Treatment of Pulmonary Disorders},
  author={Dariusz Zakrzewicz and Anna Zakrzewicz and Klaus Theo Preissner and Philipp Markart and Malgorzata Wygrecka},
  booktitle={International journal of molecular sciences},
  year={2012}
}
Protein arginine methylation is a novel posttranslational modification that plays a pivotal role in a variety of intracellular events, such as signal transduction, protein-protein interaction and transcriptional regulation, either by the direct regulation of protein function or by metabolic products originating from protein arginine methylation that influence nitric oxide (NO)-dependent processes. A growing body of evidence suggests that both mechanisms are implicated in cardiovascular and… CONTINUE READING

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