Protein Alterations in Infiltrating Ductal Carcinomas of the Breast as Detected by Nonequilibrium pH Gradient Electrophoresis and Mass Spectrometry

@article{Kabbage2008ProteinAI,
  title={Protein Alterations in Infiltrating Ductal Carcinomas  of the Breast as Detected by Nonequilibrium pH Gradient Electrophoresis and Mass Spectrometry},
  author={Maria Kabbage and Karim Chahed and Bechr Hamrita and Christelle Lemaitre Guillier and Mounir Trim{\`e}che and Sami Remadi and Johan Hoebeke and Lotfi Chouchane},
  journal={Journal of Biomedicine and Biotechnology},
  year={2008},
  volume={2008},
  pages={23 - 47}
}
Improvement of breast-cancer detection through the identification of potential cancer biomarkers is considered as a promising strategy for effective assessment of the disease. The current study has used nonequilibrium pH gradient electrophoresis with subsequent analysis by mass spectrometry to identify protein alterations in invasive ductal carcinomas of the breast from Tunisian women. We have identified multiple protein alterations in tumor tissues that were picked, processed, and… CONTINUE READING