Protein 4.1R regulates cell adhesion, spreading, migration and motility of mouse keratinocytes by modulating surface expression of beta1 integrin.

@article{Chen2011Protein4R,
  title={Protein 4.1R regulates cell adhesion, spreading, migration and motility of mouse keratinocytes by modulating surface expression of beta1 integrin.},
  author={Lixiang Chen and Richard Anthony Hughes and Anthony J. Baines and J. G. Conboy and Narla Mohandas and Xiuli An},
  journal={Journal of cell science},
  year={2011},
  volume={124 Pt 14},
  pages={2478-87}
}
Protein 4.1R is a membrane-cytoskeleton adaptor protein that has diverse roles in controlling the cell surface expression and/or function of transmembrane proteins, and in organizing F-actin. 4.1R is expressed in keratinocytes, but its role in these cells has not been explored. Here, we have investigated the role of 4.1R in skin using 4.1R(-/-) mice. Cell… CONTINUE READING