Protein:protein aggregation induced by protein oxidation.


When the level of reactive oxygen species (ROS) in cells exceeds a genetically coded defense capacity, the cells experience damage to vital components such as DNA, proteins and lipids that leads to non-specific interactions and the production of a series of high molecular weight protein aggregates. The dynamics of oxidative stress induced aggregation were… (More)
DOI: 10.1016/j.jchromb.2008.04.025


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