Protective role of the novel hybrid 3,5-dipalmitoyl-nifedipine in a cardiomyoblast culture subjected to simulated ischemia/reperfusion.

@article{SantaHelena2017ProtectiveRO,
  title={Protective role of the novel hybrid 3,5-dipalmitoyl-nifedipine in a cardiomyoblast culture subjected to simulated ischemia/reperfusion.},
  author={Eduarda Santa-Helena and Stefanie Teixeira and Micheli Rosa de Castro and Diego da Costa Cabrera and Caroline da Ros Montes D'Oca and Marcelo G M D'oca and Ana Paula de Souza Votto and Luiz eduardo maia Nery and Carla Amorim Neves Gonçalves},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={2017},
  volume={92},
  pages={356-364}
}
This work investigated the acute effects of the calcium channel blocker nifedipine and its new fatty hybrid derived from palmitic acid, 3,5-dipalmitoyl-nifedipine, compared to endocannabinoid anandamide during the process of inducing ischemia and reperfusion in cardiomyoblast H9c2 heart cells. The cardiomyoblasts were treated in 24 or 96-well plates… CONTINUE READING