Protective role of gamma interferon in experimental pulmonary paracoccidioidomycosis.


We have developed a murine model of pulmonary infection by Paracoccidioides brasiliensis in which resistance was associated with immunological activities governed by gamma interferon (IFN-gamma). To better characterize this model, we measured type 1 and type 2 cytokines in the lungs and investigated the effect of endogenous IFN-gamma depletion by monoclonal… (More)


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@article{Cano1998ProtectiveRO, title={Protective role of gamma interferon in experimental pulmonary paracoccidioidomycosis.}, author={Luz Elena Cano and Suely Sanae Kashino and Celina Arruda and Denise C Andr{\'e} and Cynthia F. Xidieh and L{\'u}cia Mary Singer-Vermes and Celid{\'e}ia Aparecida Coppi Vaz and Ekard Burger and Vera L{\'u}cia Garcia Calich}, journal={Infection and immunity}, year={1998}, volume={66 2}, pages={800-6} }