Protective role of G-CSF in dextran sulfate sodium-induced acute colitis through generating gut-homing macrophages.

Abstract

Granulocyte colony-stimulating factor (G-CSF) is a pleiotropic cytokine best known for its role in promoting the generation and function of neutrophils. G-CSF is also found to be involved in macrophage generation and immune regulation; however, its in vivo role in immune homeostasis is largely unknown. Here, we examined the role of G-CSF in dextran sulfate… (More)
DOI: 10.1016/j.cyto.2015.11.025

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