Protective immunity to malaria and anti-erythrocyte autoimmunity.

  title={Protective immunity to malaria and anti-erythrocyte autoimmunity.},
  author={William Jarra},
  journal={Ciba Foundation symposium},
The intraerythrocytic development of malaria parasites results in considerable modification and destruction of erythrocytes. This may lead to the breaking of tolerance such that immune recognition of 'self' or 'modified self' erythrocyte antigens by B or T lymphocytes occurs. Such recognition may be a vital factor in the induction of protective immunity even though it may also cause immunopathology. Serological and immunocytochemical assays have been used to demonstrate, in the serum of… CONTINUE READING



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