Protective immunity against bovine leukaemia virus (BLV) induced in carrier sheep by inoculation with a vaccinia virus-BLV env recombinant: association with cell-mediated immunity.

Abstract

The effects of vaccination of sheep with a recombinant vaccinia virus (rVV) expressing the bovine leukaemia virus (BLV) envelope glycoprotein (gp60) were studied by determining BLV titres in peripheral blood leukocytes after vaccination and challenge. The proliferation of BLV was suppressed markedly, not only when rVV was inoculated prior to challenge with… (More)

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@article{Ohishi1991ProtectiveIA, title={Protective immunity against bovine leukaemia virus (BLV) induced in carrier sheep by inoculation with a vaccinia virus-BLV env recombinant: association with cell-mediated immunity.}, author={Kohshi Ohishi and Hiroko Suzuki and Tetsuo Yamamoto and Toru Maruyama and Kenji Miki and Yoshiya Ikawa and Shigeru Numakunai and K Okada and Koichi Ohshima and M Sugimoto}, journal={The Journal of general virology}, year={1991}, volume={72 ( Pt 8)}, pages={1887-92} }