Protective immune response against Toxoplasma gondii elicited by a novel yeast-based vaccine with microneme protein 16.

@article{Wang2018ProtectiveIR,
  title={Protective immune response against Toxoplasma gondii elicited by a novel yeast-based vaccine with microneme protein 16.},
  author={Long-Jiang Wang and Ting Xiao and Chao Xu and Jin Li and Gong-zhen Liu and Kun Yin and Yong Cui and Qing-kuan Wei and Bing-cheng Huang and Hui Sun},
  journal={Vaccine},
  year={2018},
  volume={36 27},
  pages={
          3943-3948
        }
}
Toxoplasma gondii is an obligate intracellular protozoan that can invade all eukaryotic cells and infect all warm-blood animals, causing the important zoonosis toxoplasmosis. Invasion of host cells is the key step necessary for T. gondii to complete its life cycle and microneme proteins play an important role in attachment and invasion of host cells. Microneme protein 16 (TgMIC16) is a new protective protein in T. gondii and belongs to transmembrane microneme proteins (TM-MIC). The TM-MICs are… CONTINUE READING
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