Protective human immunity as a vaccine discovery tool for falciparum malaria.

@article{Nixon2005ProtectiveHI,
  title={Protective human immunity as a vaccine discovery tool for falciparum malaria.},
  author={Christian P Nixon and Jennifer Frances Friedman and Paul Mark Knopf and Patrick E Duffy and Jonathan D. Kurtis},
  journal={Transfusion},
  year={2005},
  volume={45 2 Suppl},
  pages={
          81S-87S
        }
}
BACKGROUND Plasmodium falciparum malaria remains a leading cause of morbidity and mortality in developing countries, and malaria-associated severe anemia is the major factor driving the high transfusion requirements in pediatric populations living in endemic areas. STUDY DESIGN AND METHODS In this report, we identify and evaluate the targets of naturally acquired protective antibody responses in a cohort of n = 143 male volunteers residing in a P. falciparum holoendemic area of western Kenya… CONTINUE READING
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