Protective effects of yindanxinnaotong capsule in a rat model of myocardial ischemia/reperfusion injury.

  title={Protective effects of yindanxinnaotong capsule in a rat model of myocardial ischemia/reperfusion injury.},
  author={Wan-dan Wang and Lan Wang and Hongjun Yang and Jian-lu Wang and Xiao-jie Yin and Haiyu Xu and Long Cheng and Ri-xin Liang},
  journal={Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan},
  volume={34 6},
Cardioprotective role of methanolic extract of bark of Terminalia arjuna against in-vitro model of myocardial ischemic-reperfusion injury
In the methanolic extract of the bark powder of Terminalia arjuna treatment groups, both the doses had better recovery of myocardial function, with significant reduction in TBARS, and rise in SOD, GSH, catalase were observed.
miR-210 inhibits oxidative stress damage in myocardial cell injury model
Over-expression of miR-210 could significantly inhibit oxidative stress damage in H9c2 cells, and this study is to investigate the mechanism in myocardial cell injury induced by oxidative stress.
Effects of microRNA-139 on myocardial cell injury induced by oxidative stress.
The oxidative stress injury could be inhibited after increasing the expression of miR-139-5-p, which could be related with the elimination of intracellular oxidative stress products and the resistance to apoptosis through AKT/GSK-3β signaling pathway.
Yindanxinnaotong, a Chinese compound medicine, synergistically attenuates atherosclerosis progress
Overall, these results demonstrated that YD intervention relieves atherosclerosis through regulating lipids, reducing lipid particle deposition in the endothelial layer of artery, enhancing antioxidant power, and repressing inflammation activity by inhibiting the nuclear factor-kappa B signal pathway.
Downregulation of miR-122 attenuates hypoxia/reoxygenation (H/R)-induced myocardial cell apoptosis by upregulating GATA-4.
The Clinical Efficacy of Yindanxinnaotong Soft Capsule in the Treatment of Stroke and Angina Pectoris: A Meta-Analysis
YD is effective in the treatment of cardiovascular diseases (angina pectoris and stroke) in adults, and WCM plus YD therapeutic regimen can significantly improve the effective rate in the clinic.
Identification of absorbed constituents and evaluation of the pharmacokinetics of main compounds after oral administration of yindanxinnaotong by UPLC-Q-TOF-MS and UPLC-QqQ-MS
Yindanxinnaotong capsule (YDXNT), a traditional Chinese formula, has been used to treat cardio-cerebrovascular diseases for several decades. Previous research has focused on evaluating the
Complementary Role of Herbal Medicine and Exercise in Cardiovascular Disease Prevention and Management: A Review of Evidence.
Evidence of complementary role of herbal medicine and exercise is emerging from animal studies is emerging, and more robust clinical studies on proven risk factors are needed before they can be recommended for clinical practice.
Identification and evaluation of the chemical similarity of Yindan xinnaotong samples by ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry fingerprinting.
In this study, ultra high performance liquid chromatography coupled with time-of-flight mass spectrometry was used to identify the chemical components of Yindan xinnaotong soft capsules and a fingerprint analysis was conducted to evaluate the uniformity of the quality.


BNC Protects H9c2 Cardiomyoblasts from H2O2-Induced Oxidative Injury through ERK1/2 Signaling Pathway
The data demonstrated that BNC protects H9c2 cardiomyoblasts from H2O2-induced oxidative injury by increasing antioxidant abilities, activating ERK1/2, and blocking Ca2+-dependent and mitochondria-mediated apoptosis.
BNC Protects H 9 c 2 Cardiomyoblasts from H 2 O 2-Induced Oxidative Injury through ERK 1 / 2 Signaling Pathway
The potency of BNC for protecting H9c2 cells from oxidative damage is comparable to that of trimetazidine, and preconditioning enhanced antioxidant function by increasing antioxidant abilities, activating ERK1/2, and blocking Ca-dependent and mitochondria-mediated apoptosis.
Baicalin attenuates acute myocardial infarction of rats via mediating the mitogen-activated protein kinase pathway.
The results suggest that the baicalin's cardioprotection associates with mediation of MAPK cascades in acute myocardial infarction of rats.
Progress of Toll-like Receptor 2 and 4 in Myocardial Ischemia/reperfusion Injury
New insight is provided into the signal pathway of the TLR in the I/R injury, which is a key determinant of the left ventricular remodeling and heart failure.
Dynasore Protects Mitochondria and Improves Cardiac Lusitropy in Langendorff Perfused Mouse Heart
Dynasore protects cardiac lusitropy and limits cell damage through a mechanism that maintains mitochondrial morphology and intracellular ATP in stressed cells and can have clinical benefit by positively influencing the energetics of diastolic dysfunction.
Efficacy Observation of Yindanxinnaotong Soft Capsules Combined with 3 Chemicals for Coronary Disease Angina Pectoris
The therapeutic effect is improved by using Yindanxinnaotong Soft Capsules combined with isesorbide 5-mononitrate sustained release tablets,bisoprolol fumarate tablets,amlodipine besylate tablets for coronary disease angina pectoris.
Research Progress on Myocardial Ischemia Reperfusion Injury
The prevention of myocardial ischemia reperfusion injury includes ischemic preconditioning,ischemic post-processing,anti-inflammatory treatment,improving cardiac metabolism,etc.It is summarized now.
The clinical observation of Danshenchuanxion - gqin injection combined with Yindanxinnaotong capsule to treat coronary heart disease and angina pectoris
  • Zhong Guo Xian Dai Yao Wu Ying Yong
  • 2012