Protective effects of vitamins C and E against gamma-ray-induced chromosomal damage in mouse.

@article{Sarma1993ProtectiveEO,
  title={Protective effects of vitamins C and E against gamma-ray-induced chromosomal damage in mouse.},
  author={L Sarma and Parthasaratmy Chenna Kesavan},
  journal={International journal of radiation biology},
  year={1993},
  volume={63 6},
  pages={759-64}
}
The effects of vitamins C and E on bone marrow chromosomes of the mouse exposed to 1 Gy of whole-body gamma-irradiation were studied. These vitamins, dissolved in water/peanut oil, were administered orally as acute doses, either 2 h before, immediately after, or 2 h after irradiation. Both vitamins significantly reduced the frequencies of micronuclei and chromosomal aberrations in bone marrow cells; radioprotection by vitamin E was, however, appreciably greater than that afforded by vitamin C… CONTINUE READING

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