• Corpus ID: 88059858

Protective effects of total flavonoids of Sarcandra glabra(Thunb.)Nakai on potassium bromate-induced kidney damage in mice

@article{Wenyan2012ProtectiveEO,
  title={Protective effects of total flavonoids of Sarcandra glabra(Thunb.)Nakai on potassium bromate-induced kidney damage in mice},
  author={Wu Wen-yan},
  journal={Strait Pharmaceutical Journal},
  year={2012}
}
  • Wu Wen-yan
  • Published 2012
  • Biology
  • Strait Pharmaceutical Journal
OBJECTIVE To investigate the protective effects of total flavonoids of Sarcandra glabra(Thunb.)Nakai(TFS) on potassium bromate(KBrO3)-induced kidney damage in mice.METHODS The kidney damage model was established by receiving a single ip administration of 200mg·kg-1 KBrO3 in mice.Serum creatinine level and the contents of glutathione(GSH) in kidneys were determined by high performance liquid chromatography(HPLC).Spectrophotometric method was performed to detect the levels of malondialdehyde(MDA…