Protective effects of sirolimus by attenuating connective tissue growth factor expression in human chronic allograft nephropathy.

Abstract

BACKGROUND Chronic allograft nephropathy (CAN) remains a great challenge for the transplant clinician. The introduction of sirolimus (RAPA) with cyclosporine (CsA) reduction maybe shed new light to improve graft survival. The aim of this study was to investigate the overall effects of sirolimus conversion on biopsy-proven CAN. METHODS One hundred and ten… (More)

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Cite this paper

@article{Liu2007ProtectiveEO, title={Protective effects of sirolimus by attenuating connective tissue growth factor expression in human chronic allograft nephropathy.}, author={Mingya Liu and Wendy Y L Zhang and Min Gu and C. Yin and Wende Zhang and Qi Lv and D. Xu}, journal={Transplantation proceedings}, year={2007}, volume={39 5}, pages={1410-5} }