Protective effects of silybin and analogues against X-ray radiation-induced damage.

  title={Protective effects of silybin and analogues against X-ray radiation-induced damage.},
  author={Haiying Fu and Mingzhang Lin and Yosuke Katsumura and Akinari Yokoya and Kuniki Hata and Yusa Muroya and Kentaro Fujii and Naoya Shikazono},
  journal={Acta biochimica et biophysica Sinica},
  volume={42 7},
Silybin (SLB) and similar analogues, namely, hesperetin (HESP), naringenin (NAN) and naringin (NAR), are believed to be active constituents of natural flavonoids that have been reported as chemopreventive agents for certain cancers. Moreover, SLB and analogues have been determined to fast repair DNA bases from oxidative damage by pulse radiolysis techniques. The present study was designed to evaluate the protective effects of SLB and analogues on soft X-ray-induced damage to plasmid DNA in… 

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