Protective effects of metformin on reproductive function in obese male rats induced by high-fat diet


The study aims to elucidate the changes in testicular spermatogenic function in high-fat diet (HFD)-induced obese rats and to evaluate the protective effects of metformin intervention. Male Sprague–Dawley rats (n = 18) were randomly divided into a control group (standard diet), an HFD group, and a metformin group (HFD + metformin at 100 mg/kg, once daily by… (More)
DOI: 10.1007/s10815-015-0506-2