Protective effects of melatonin on testicular torsion/detorsion-induced ischemia-reperfusion injury in rats.

@article{Kanter2010ProtectiveEO,
  title={Protective effects of melatonin on testicular torsion/detorsion-induced ischemia-reperfusion injury in rats.},
  author={Mehmet Kanter},
  journal={Experimental and molecular pathology},
  year={2010},
  volume={89 3},
  pages={314-20}
}
Testicular torsion causes an enhanced formation of reactive oxygen species, which contributes to the pathophysiology of tissue damage. The aim of this study was to investigate the protective effect of melatonin on testicular torsion/detorsion-induced ischemia-reperfusion (I/R) injury. A total of 24 male Wistar albino rats were divided into three groups of 8 animals each: control, I/R, and I/R treated with melatonin. The ischemia period was 5 h and orchiectomy was performed after 5 h of… CONTINUE READING

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