Protective effects of ischemic postconditioning against hypoxia-reoxygenation injury and hydrogen peroxide-induced damage in isolated rat hearts.

@article{Li2006ProtectiveEO,
  title={Protective effects of ischemic postconditioning against hypoxia-reoxygenation injury and hydrogen peroxide-induced damage in isolated rat hearts.},
  author={Shanshuang Li and Jinrong Wu and Makino Watanabe and Chunzi Li and Takao Okada},
  journal={Experimental and clinical cardiology},
  year={2006},
  volume={11 4},
  pages={280-5}
}
OBJECTIVE Ischemic preconditioning (PR) protects hearts from ischemia-reperfusion injury. The purpose of the present study was to examine the protective effect of PR and postconditioning (PT) against hypoxia-reoxygenation injury and H(2)O(2)-induced damage in isolated rat hearts. METHODS AND RESULTS Hearts from male Sprague-Dawley rats were perfused with Krebs-Henseleit solution by Langendorff methods and subjected to two protocols. In protocol A, control hearts underwent 45 min of hypoxia… CONTINUE READING
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