• Corpus ID: 52029333

Protective effects of icariin on lipopolysaccharide-induced acute renal injury in mice

  title={Protective effects of icariin on lipopolysaccharide-induced acute renal injury in mice},
  author={Xiang Ping Meng and Li Meng and Jingshun Jin and Chou Xu and Xiaoning Zhang},
Objective: Sepsis can cause serious acute kidney injury inbacterium infected patients, especially for intensive care patients. Icariin is a bioactive flavonoid, which has renal protection and anti-inflammation effects. This study investigated the mechanism underlying the attenuation of Lipopolysaccharide (LPS) induced renal injury by icariin. Methods: ICRmice were treated with LPS (25 mg/kg) with or without treatment with icariin (20 or 40 mg/kg for three days). Renal function, histological… 
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