Protective effects of hesperidin on concanavalin A-induced hepatic injury in mice.

@article{Li2014ProtectiveEO,
  title={Protective effects of hesperidin on concanavalin A-induced hepatic injury in mice.},
  author={G. Li and Mao-jian Chen and C. Wang and Hao Nie and Wen-jian Huang and Tingyun Yuan and Ting Sun and Ke-gang Shu and Chang-fu Wang and Q. Gong and Shao-Qian Tang},
  journal={International immunopharmacology},
  year={2014},
  volume={21 2},
  pages={
          406-11
        }
}
Hesperidin (HDN) is a citrus bioflavonoid, which widely exists in many plants. Previous researches have proved that HDN has several functions such as anti-oxidant, anti-tumor, anti-inflammatory, immune regulation and so on. In the present study, we explored the protective effects of HDN on concanavalin A (Con A)-induced hepatic injury. Acute hepatic injury model was established successfully by intravenous administration of Con A (15 mg/kg) in male C57BL/6 mice, and HDN was pretreated for 10… Expand
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