Protective effects of ellagic and chlorogenic acids against oxidative stress in PC12 cells.

@article{Pavlica2005ProtectiveEO,
  title={Protective effects of ellagic and chlorogenic acids against oxidative stress in PC12 cells.},
  author={Sanja Pavlica and Rolf Gebhardt},
  journal={Free radical research},
  year={2005},
  volume={39 12},
  pages={1377-90}
}
Following exposure of differentiated neuronal PC12 cells to either t-BHP, hydrogen peroxide (H2O2) or FeSO4 various kinds of reactive oxygen species (ROS) are generated leading to oxidative injury. The protective effects of two plant polyphenols, ellagic (EC) and chlorogenic acid (CGA), as well as of two metabolites, caffeic acid (CA) and ferulic acid (FA), were investigated in preincubation and coincubation experiments with respect to the following parameters: prevention of cell death, GSH… CONTINUE READING
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