Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice

Abstract

To investigate the potential protective effects of chlorogenic acid (CGA) on acute liver injury caused by lipopolysaccharide (LPS) in mice. C57BL/6J mice were pretreated with CGA (50 mg/kg, intraperitoneally) once per day for 5 days before an overnight LPS challenge (30 mg/kg, intraperitoneally). Severity of liver injury was assessed by histological… (More)
DOI: 10.1007/s00011-010-0199-z

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@article{Xu2010ProtectiveEO, title={Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice}, author={Yuexin Xu and Jingwen Chen and Xiao Yu and W. Tao and Fengrong Jiang and Zhimin Yin and Chang Liu}, journal={Inflammation Research}, year={2010}, volume={59}, pages={871-877} }