Protective effects of N-acetylcysteine against cadmium-induced damage in cultured rat normal liver cells.

@article{Odewumi2011ProtectiveEO,
  title={Protective effects of N-acetylcysteine against cadmium-induced damage in cultured rat normal liver cells.},
  author={Caroline O Odewumi and Veera L.D. Badisa and Uyen T Le and Lekan M. Latinwo and Christopher O Ikediobi and Ramesh Babu Badisa and Selina F. Darling-Reed},
  journal={International journal of molecular medicine},
  year={2011},
  volume={27 2},
  pages={243-8}
}
In this study, the protective effects of N-acetylcysteine (NAC), a precursor of reduced glutathione, were studied by measuring the viability, the levels of antioxidant enzymes, and by analyzing the cell cycle in cadmium (Cd)-treated rat liver cells. The cells were treated with 150 µM CdCl2 alone or co-treated with 150 µM CdCl2 and 5 mM NAC (2 h pre-, simultaneous or 2 h post-treatment) for 24 h. The viability of the cells treated with 150 µM CdCl2 alone decreased to 40.1%, while that of the… CONTINUE READING
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Effects of long - term low - dose cadmium exposure on genomic DNA Methylation in human embryo lung fibroblast cells

  • J Gaofeng, X Lei, +4 authors W Lei
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