Protective effects of N-acetylcysteine against monosodium glutamate-induced astrocytic cell death.

@article{Park2014ProtectiveEO,
  title={Protective effects of N-acetylcysteine against monosodium glutamate-induced astrocytic cell death.},
  author={Euteum Park and Kyoung Hwan Yu and Do Kyung Kim and Seung Kim and Kumar Sapkota and Sung-Jun Kim and Chun Sung Kim and Hong Sung Chun},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2014},
  volume={67},
  pages={1-9}
}
Monosodium glutamate (MSG) is a flavor enhancer, largely used in the food industry and it was reported to have excitotoxic effects. Higher amounts of MSG consumption have been related with increased risk of many diseases, including Chinese restaurant syndrome and metabolic syndromes in human. This study investigated the protective effects of N-acetylcysteine (NAC) on MSG-induced cytotoxicity in C6 astrocytic cells. MSG (20 mM)-induced reactive oxygen species (ROS) generation and apoptotic cell… CONTINUE READING
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