Protective effects of Mangifera indica L extract (Vimang), and its major component mangiferin, on iron-induced oxidative damage to rat serum and liver.

@article{PardoAndreu2008ProtectiveEO,
  title={Protective effects of Mangifera indica L extract (Vimang), and its major component mangiferin, on iron-induced oxidative damage to rat serum and liver.},
  author={Gilberto L Pardo-Andreu and Mariela Forrellat Barrios and Carlos Curti and Ivones Hern{\'a}ndez and Nelson Merino and Yeny Lemus and Ioanna Mart{\'i}nez and Annia Ria{\~n}o and Ren{\'e} Delgado},
  journal={Pharmacological research},
  year={2008},
  volume={57 1},
  pages={79-86}
}
In vivo preventive effects of a Mangifera indica L extract (Vimang) or its major component mangiferin on iron overload injury have been studied in rats given respectively, 50, 100, 250 mg kg(-1) body weight of Vimang, or 40 mg kg(-1) body weight of mangiferin, for 7 days prior to, and for 7 days following the administration of toxic amounts of iron-dextran. Both Vimang or mangiferin treatment prevented iron overload in serum as well as liver oxidative stress, decreased serum and liver lipid… CONTINUE READING

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Both Vimang or mangiferin treatment prevented iron overload in serum as well as liver oxidative stress , decreased serum and liver lipid peroxidation , serum GPx activity , and increased serum and liver GSH , serum SOD and the animals overall antioxidant condition .
Both Vimang or mangiferin treatment prevented iron overload in serum as well as liver oxidative stress , decreased serum and liver lipid peroxidation , serum GPx activity , and increased serum and liver GSH , serum SOD and the animals overall antioxidant condition .
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