Corpus ID: 8663588

Protective effects of I(1)-antihypertensive agent moxonidine against neurogenic cardiac arrhythmias in halothane-anesthetized rabbits.

@article{Poisson2000ProtectiveEO,
  title={Protective effects of I(1)-antihypertensive agent moxonidine against neurogenic cardiac arrhythmias in halothane-anesthetized rabbits.},
  author={D. Poisson and M. Christen and F. Sannajust},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={2000},
  volume={293 3},
  pages={
          929-38
        }
}
Numerous studies have addressed the antihypertensive properties of I(1)-imidazoline receptor agonists such as moxonidine, but very few authors examined their cardiac antiarrhythmic potency. Due to the important role of the sympathetic nervous system in the genesis of neurogenic cardiac arrhythmias, we investigated the antiarrhythmic effects of moxonidine and compared them to those of propranolol in an experimental model of neurogenic arrhythmias. Chronic bipolar electrodes were implanted within… Expand
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