Corpus ID: 195742481

Protective effects of H 2 S inhalation on cerebral resuscitation in cardiac arrest rats associated with modulation of inflammatory cytokines and p 38 MAPK signaling pathways in brain tissue

  title={Protective effects of H 2 S inhalation on cerebral resuscitation in cardiac arrest rats associated with modulation of inflammatory cytokines and p 38 MAPK signaling pathways in brain tissue},
  author={Minfeng Tong and Xing Wan and Guodong He and Jihong Liu and Fan Yang},
Objective: The aim of this study was to evaluate the protective effects of hydrogen sulfide (H2S) inhalation on cerebral resuscitation in cardiac arrest rats and its effects on inflammatory cytokines and p38MAPK signaling pathways in brain tissue. Methods: One hundred male Sprague-Dawley rats were randomly divided into 5 groups: sham-operated, cardiac arrest resuscitation, H2S, shallow hypothermia, and H2S + shallow hypothermia. Enzymelinked immunosorbent assay (ELISA) was used to detect the… Expand

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