Corpus ID: 8523971

Protective effects of Ginkgo biloba extract against lysophosphatidylcholine-induced vascular endothelial cell damage.

  title={Protective effects of Ginkgo biloba extract against lysophosphatidylcholine-induced vascular endothelial cell damage.},
  author={Jiandong Chen and W Z Chen and H L Huang and L X Chen and Z Z Xie and Bing-yang Zhu},
  journal={Zhongguo yao li xue bao = Acta pharmacologica Sinica},
  volume={19 4},
  • J. Chen, W. Z. Chen, +3 authors B. Zhu
  • Published 1 July 1998
  • Chemistry, Medicine
  • Zhongguo yao li xue bao = Acta pharmacologica Sinica
AIM To study the protective effects of Ginkgo biloba extract (GbE) against endothelial cell damage induced by lysophosphatidylcholine (LPC). METHODS The vasorelaxation response to acetylcholine (ACh) were investigated in the isolated rabbit thoracic aorta. Lipid peroxidation products were determined by measuring thiobarbituric acid reactive substance. RESULTS GbE attenuated the inhibition of vasorelaxation response to ACh and prevented the LPC-induced increase of malondialdehyde (MDA… Expand
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