Protective effects of Ginkgo biloba extract against lysophosphatidylcholine-induced vascular endothelial cell damage.
@article{Chen1998ProtectiveEO, title={Protective effects of Ginkgo biloba extract against lysophosphatidylcholine-induced vascular endothelial cell damage.}, author={J X Chen and W Z Chen and H L Huang and L X Chen and Z Z Xie and Bo Zhu}, journal={Zhongguo yao li xue bao = Acta pharmacologica Sinica}, year={1998}, volume={19 4}, pages={ 359-63 } }
AIM
To study the protective effects of Ginkgo biloba extract (GbE) against endothelial cell damage induced by lysophosphatidylcholine (LPC).
METHODS
The vasorelaxation response to acetylcholine (ACh) were investigated in the isolated rabbit thoracic aorta. Lipid peroxidation products were determined by measuring thiobarbituric acid reactive substance.
RESULTS
GbE attenuated the inhibition of vasorelaxation response to ACh and prevented the LPC-induced increase of malondialdehyde (MDA…
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